Phd Student Cover Letter Examples And Template
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Phd Student Cover Letter Examples
PhD student Cover Letter At Max Planck institution
Max Planck institution
Germany
Molecular biology techniques- pcr
By Joy panchal
Phd student Cover Letter At Technical university of Munich
Technical university of Munich
Germany
All Analytical Instruments
Ms Word
Ms office
PowerPoint
Ms excel
By Saista parmar
PhD student Cover Letter At Utrecht University
Utrecht University
Netherlands
Mammalian cell culture
3D organoids & spheroids
ELISA
Flow cytometry
Fluorescence microscope
By Balaji
PhD Student Cover Letter At PASTERKAMP LAB
PASTERKAMP LAB
Developmental and molecular neurobiology: studies on the development and remodelling of neural circuits in several different brain regions
including the dopamine
cortical
hippocampal and motor systems. Mouse genetics: generation of knockout
knockin and transgenic mouse lines and mouse in utero electroporation. Biochemistry: (in vivo) proteomics approaches for the identification and characterization of novel protein-protein interactions in neurons. Cell biology and microscopy: tissue culture approaches in combination with cellular imaging (calcium
confocal
lightsheet) for studying dendrite and axon development and synapse formation. Non-coding RNA: using different approaches (e.g. arrays
RNAseq
high-throughput screening) we are studying the role of non-coding RNAs (microRNA and circular RNA) during neural circuit development and disease. IPSC neurons and organoids: We have set up and are coordinating a new facility within the UMC Utrecht
the MIND facility
for generating humanized models to study brain disease. These models include IPSC neuron cultures (motor
cortical and other) and organoids (cerebral and cortical) in combination with genome editing techniques (CRISPR/CAS). Behaviour: for performing phenotypical analyses of epilepsy and neuromuscular disease models we perform EEG recording
Rotarod and grip strength analyses
and other behavioural tests. Neurological disease: in collaboration with different clinical partners we are dissecting disease mechanisms of diseases such as epilepsy
ALS and SMA. The use and generation of induced pluripotent stem cell (IPSC)-generated cells or tissues has increased exponentially. The possibility of generating patient-derived IPSC lines followed by differentiation into desired cell types or tissues provides new and ground-breaking insights into disease mechanisms and can facilitate the development of therapeutic approaches. We use IPSC approaches to generate neurons
(micro)glial cells and non-neural cells for different translational projects. For example
motor neurons and muscle cells for research into ALS. Differentiated cultures generated from (gene mutation corrected) control and patient IPSCs are subjected to numerous analyses
including electrophysiology (patch clamp)
calcium imaging
immunocytochemistry and (single cell) RNAseq. In addition to isolated neuronal or glial cultures
organ-on-a-chip technology is used to reconstruct neural circuits
for example the neuromuscular junction. Furthermore
genome editing approaches
such as CRISPR/CAS9
are used to generate isogenic controls or cell lines carrying specific mutations. IPSCs are also used to generate various types of brain organoids allowing analysis of neuronal and glial cell morphology and function in a three-dimensional environment
for example for studying ALS and Alzheimer’s disease. Analysis of neuronal morphology is facilitated by Ultramicroscope lightsheet imaging present in our lab. Our human in vitro modelling studies are supported by different funding agencies including Stichting ALS Nederland
Health Holland
Horizon Europe (YouthGEMS) and others.• Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis.Our research focuses on understanding 1) the molecular mechanisms involved in the development of neuronal circuitry
and 2) the disease mechanisms responsible for changes in or loss of neuronal connectivity during motor neuron disease (ALS) and other neurodegenerative diseases. RNA biology (e.g. non-coding RNAs)
(single cell) omics
mouse genetics
humanized cell models (iPSC
organoids
microfluidics)
molecular cell biology
and (light sheet) microscopy play a central role in many of our projects.
By Melike Cansel EREN
PhD student Cover Letter At Single Ventricle Disease PhD
Single Ventricle Disease PhD
By JHM
phd student Cover Letter At ABC
ABC
By Darsha Jayathunga
PhD student Cover Letter At TextAi
TextAi
By Jack
PhD Student Cover Letter At Melbourne University
Melbourne University
Skills & Qualifications • Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. Our laboratory focuses on the study of human pluripotent stem cells for modelling neurodegenerative diseases. The difficulty in obtaining brain or ocular tissue from living people is a major barrier to developing new treatments for neurodegenerative disease. We can now generate stem cells from adult tissue
and these “induced pluripotent stem cells” (iPSCs) represent a powerful disease modelling tool. Generating iPSCs directly from patients allows cells to be differentiated into specific cells of interest for disease modelling
drug screening
and understanding of fundamental pathogenic mechanisms. We differentiate iPSCs into various cell types of the nervous system
as monolayers or as organoids. Using these cells
we model age-related macular degeneration
glaucoma
inherited retinal dystrophies and optic neuropathies
in order to establish the molecular events leading to disease progression and aspects of neurodegeneration. We also use gene editing technology for correction of monogenic diseases of the retina and the optic nerve. The CRISPR system is used by bacteria to counter viral intrusion and has been adapted to allow efficient editing of the mammalian nuclear genome. CRISPR-based technology is being heralded as a relatively straightforward technology for in vitro correction of genetic mutations in patient-specific cells and is particularly attractive for treating inherited diseases caused by genes with very specific spatial and stoichiometric expression
such as those found in many of the monogenic diseases we study. We use our unique cohort of patients with distinct monogenic inherited retinal dystrophies and iPSC technology to directly study the utility of genomic editing and correction. Service Node - Phenomics Australia Phenomics Australia is a forward-thinking research infrastructure provider enabling research discovery and high-impact healthcare outcomes in precision medicine. Through openly accessible service delivery centres
we offer specialised infrastructure
research services and technical expertise dedicated to advancing our fundamental understanding of health and disease
and enabling next-generation innovations in healthcare and therapeutic development to benefit all Australians. We are supported by the Australian Government through the National Collaborative Research Infrastructure Strategy
(NCRIS). NCRIS supports Australia’s research capability by investing in research infrastructure and making it accessible to researchers across the nation. Services: Phenomics Australia provides a broad panel of in vivo and in vitro genome engineering and disease modelling
functional genomics and high-throughput screening
biobanking and pathology services and technical expertise
for discovery and a new understanding of the molecular basis of disease to benefit all Australians. More information about Phenomics Australia services can be found here. As a service node of Phenomics Australia
we provide on-demand reprogramming of patient samples into iPSCs
their quality control and banking
focusing on the production of large-scale iPSC cohort. We can reprogram from various primary cell types
and with different reprogramming approaches. Our service also includes training of researchers in these procedures. Please contact our node manager Dr Maciej Daniszewski for further information. maciej.daniszewski@unimelb.edu.au Stem Cell Neuropsychiatry Group Our research leverages stem cell models to study the development and function of the brain
both in health and mental illness. Studying the brain
however
presents several challenges
including its inaccessible and complex nature
consisting of numerous interrelated regions and an enormous number of cells
as well as the uniqueness of each individual's brain
making it difficult to establish universal conclusions. We generate stem cells from adult human tissue
specifically induced pluripotent stem cells (iPSCs)
to overcome some of the obstacles in studying human brain development. Utilising iPSCs
we aim to refine and advance models of neural connectivity in vitro and uncover the molecular and cellular foundations of healthy development and major psychiatric illnesses. Our research incorporates neuroimaging observations of the living human brain and brings together a diverse team with expertise in neuroscience
psychiatry
neuroimaging
and computer science. Our ultimate goal is to translate the knowledge gained from these studies into improved therapies for psychiatric illnesses. Human pluripotent stem cell-derived neurons. Cytoskeletal marker class III beta-tubulin (green)
dendritic marker microtubule associated protein 2 (red) and nuclear stain Hoechst (blue). Images by Cassandra Hoffman (PhD Candidate) Human pluripotent stem cell-derived neurons. Cytoskeletal marker class III beta-tubulin (green)
dendritic marker microtubule associated protein 2 (red) and nuclear stain Hoechst (blue). Images by Cassandra Hoffman (PhD Candidate). This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. By generating both 2D and 3D neural models from induced pluripotent stem cells (iPSCs) sourced from patients
you will tackle the complexities of human brain development research. The project involves the generation of in vitro neurodevelopmental models
their in-depth characterisation through techniques such as calcium imaging and single cell RNA sequencing
and the computational analysis of these data. The overarching goal is to unravel the molecular and cellular foundations of schizophrenia and we are dedicated to translating our research findings into groundbreaking treatments. Our multidisciplinary team
led by Dr. Maria Di Biase and Prof. Alice Pébay
brings together expertise in stem cell disease modeling
neuroscience
psychiatry
and computer science. As a part of this dynamic team
you will find your research home at the Stem Cell Disease Modelling Lab. Successful candidates will be expected to conduct high-level research
work as part of a team and contribute to publications in internationally recognised journals. Requirements: An undergraduate or graduate degree with upper class honours in neuroscience
basic science
biomedical science
or a closely related field. Priority will be given to applicants who have relevant experience in regenerative medicine/stem cell modeling
functional connectivity assays (including calcium imaging or multielectrode arrays)
or in analysing single-cell RNA sequencing data.
By Melike Cansel EREN
PhD Student Cover Letter At Karolinska Institute
Karolinska Institute
By Akshit Lohan
PhD Student Cover Letter At Gottingen
Gottingen
By Abrar
PhD student Cover Letter At university
university
By Soheila
PhD student Cover Letter At IBAB bangalore
IBAB bangalore
Bangalore
R
python
NGS
Basic bioinformatic
wet leb
By Tamalika Manna
PhD student Cover Letter At University of Amsterdam
University of Amsterdam
• Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. You are expected to: • to complete a PhD thesis within the official appointment duration of four years; • analyze an existing dataset of multi-area electrophysiological recordings with single-cell resolution in a mouse model of autism; • develop analytical methods to test the hypothesis that impaired inter-areal coordination correlates with sensory processing deficits in ASD; • assist during in-vivo multi-area electrophysiological recordings and optogenetics; • take part in the teaching effort of the group
including supervision of bachelor’s and master’s students; • write scientific manuscripts and a PhD thesis. What do we require? • a MSc in Neuroscience or a closely related field; a MSc in mathematics
physics
engineering or related topics is also possible if the candidate can demonstrate sufficient background in neuroscience; • strong scientific expertise in signal processing
brain data analysis and/or behavioral testing; • demonstrable experience in complex electrophysiological data analysis; • strong programming skills in MATLAB or Python; • experience or at least affinity with in in vivo electrophysiology and possession of an “article 9” (FELASA B) license are important assets for this position; • fluent in English
both written and spoken
By Melike Cansel EREN
phd student Cover Letter At Harvard medicl school
Harvard medicl school
By ree
PhD student Cover Letter At DTU - Technical University of Denmark
DTU - Technical University of Denmark
By Shiva Ahmadi Nasab
PhD student Cover Letter At Hertie School
Hertie School
By Ulviyya
Ph.D. Student Cover Letter At Sandip University Nashik
Sandip University Nashik
By Siddheshwar Atmaram Kadam
PhD student Cover Letter At EMBL
EMBL
By Mehul
Phd student Cover Letter At Institute of Pharmacology - Charité Universitätsmedizin Berlin
Institute of Pharmacology - Charité Universitätsmedizin Berlin
Berlin
molecular cloning
site-directed mutagenesis
reporter gene assays
ELISA assays
immunocytochemistry
cell culture
By Leonor de Buijzer
PhD student Cover Letter At Epfl
Epfl
By Nila
PhD Student Cover Letter At Institut de recherche de Montreal en biologie végétale, Montreal Botanical Garden
Institut de recherche de Montreal en biologie végétale, Montreal Botanical Garden
By Fatemeh Soroodi
PhD student Cover Letter At Danish Cancer Society
Danish Cancer Society
By Dennis Hirsch Menne
PhD Student Cover Letter At Rozeske Lab
Rozeske Lab
We use a multi-disciplinary approach to understand the neuronal mechanisms of fear and anxiety behaviours Our goal is to learn how experiences modify neuronal circuit physiology to form memories
and how these functional alterations oppose or promote flexible emotional behaviour. To identify the neuronal mechanisms of fear and anxiety states
our lab uses multiple techniques to record time-series neuronal activity during fear and anxiety behaviours. We aim to understand the neuronal circuit motifs that support fear and anxiety behaviors
with the hope that our circuit models may inform novel therapeutics to treat individuals living with mental illness. • Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. Research overview Threatening or dangerous situations create a constellation of physiological and behavioural responses. Yet
how an organism responds to a threatening situation depends on a variety of factors such as age
biological sex
past experiences
and the present spatial context. We are particularly interested in how hippocampal context/spatial representations in the brain are modified by these experiential factors to guide evolutionarily conserved emotional behaviour. Our lab specifically investigates the dynamic circuit mechanisms that generate flexible fear and anxiety states. We use multiple state-of-the-art techniques to understand how fear and anxiety are represented in the brain and define the neuronal circuits responsible for these defensive behaviours. By resolving the neuronal circuits that support defensive behaviours
our hope is for our discoveries to lead to novel therapeutics that reduce symptoms of mental illnesses such as post-traumatic stress disorder
generalized anxiety disorder
and depression. Technical approaches Behaviour Innovative fear and anxiety paradigms Learned and innate defensive behaviour Unsupervised behavioural pose estimation Circuit In vivo single unit electrophysiology Fiber photometry Microendoscope calcium imaging Anterograde and retrograde mapping of neuronal pathways Perturb Optogenetic interrogation Chemogenetic inhibition Pharmacological administration
By Melike Cansel EREN
PhD Student Cover Letter At Glia Lab
Glia Lab
• Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. Research Goals In addition to the 85 billion neurons in the brain
we find at least as many glial cells. The research focus of GliaLab is to discover physiological roles of a subtype of glial cells called astrocytes
in the awake-behaving and sleeping brain as well as identifying roles of astrocytes in brain disorders. Astrocytes serve a wide array of functions in the brain. On the one hand
they are caretakers of the brain by controlling the composition of the extracellular fluids. In particular they are key for removing excess neurotransmitter and K+ in relation to neuronal activity. Moreover
they display a rich repertoire of cellular signaling
that likely enable them to more direcly interact with neurons. Our main research interests are as follows: What are the roles of astrocytic Ca2+ signals in sleep and brain state changes? Since the discovery that astrocytes can react with and communicate by local or spreading Ca2+ elevations
a range of different mechanisms have been linked to these signals. For instance
such signals have been proposed to influence neuronal network activity by release of transmitter substances in
or close by
synapses. Similarly
astrocytic Ca2+ signals have been proposed to influence vascular tone. Currently
we're trying to outline the role of astroglial Ca2+ signals in brain/sleep state changes and in memory encoding and consolidation. How does the extracellular fluid circulate in the brain parenchyma? In 2013 a seminal paper described extracellular fluid may circulate from the perivascular spaces of artieries
through the parenchyma
before exiting the brain
taking waste products with it. This circulation system
or 'brain washing' system
was coined the 'glymphatic system'
and was proposed to play a role in Alzheimer's disease pathophysiology. To answer these questions we work with advanced imaging techniques. Most importantly
two-photon microscopy in awake head-fixed mice
in combination with electrophysiology and molecular strategies. What are the astrocytic mechanisms involved in cortical spreading depression (CSD) and epilepsy? CSD is the phenomenon underlying the perceptual disturbances of the migraine aura
and although first discovered over 70 years ago
key aspects of these events are still unknown. We are currently trying to identify the roles of astrocytes in CSD. We are also investigating putative roles of astrocytes in seizure propagation and in epileptogenesis.
By Melike Cansel EREN
PhD student Cover Letter At International Max Planck Research School SusMet in Germany
International Max Planck Research School SusMet in Germany
By Hamed Aminian
PhD student Cover Letter At Gothenburg University
Gothenburg University
Python
R
metagenomics
pipeline development
By Kaavya Venkateswaran
phd student Cover Letter At nstitute of Biophysics, Czech Academy of Sciences Research Field
nstitute of Biophysics, Czech Academy of Sciences Research Field
By Javad Zohdi
PhD Student Cover Letter At tu munic
tu munic
By asdf fda
PhD student Cover Letter At Trinity College Dublin
Trinity College Dublin
Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis.
By Melike Cansel EREN
PhD student Cover Letter At Helmholtz Center for Information Security (CISPA)
Helmholtz Center for Information Security (CISPA)
Saarbrücken, Germany
Masters in Electrical Engineering - Control (average of 18.36 ot of 20) (ranked within the top 5% of my graduating class) Python
Matlab/Simulink optimization modeling utlizing machine learning techniques Excellent ability for cooperative collaboration publish a paper in The Wind Engineering journal and some other under prepreation papers Teaching assistante for post-graduate students like optimal control theory
system identification
and linear control systems Very good communication skills in English with IELTS band overal 7.0
By Moein Sarbandi
PhD student Cover Letter At University of Luxembourg
University of Luxembourg
Luxembourg
Wet lab skills
ELISA
qPCR
Western Blot
scientific writing
By Joyce Schmit
PhD student Cover Letter At UMR INSERM 1070 & 1248
UMR INSERM 1070 & 1248
good knowledge of R
By BERRAH Racym
Ph.D. Student Cover Letter At Wageningen University and Research
Wageningen University and Research
By Muhammad Muneeb Ullah
PhD student Cover Letter At ETH Zurich
ETH Zurich
Zurich
Python
chemistry
data analysis
lithium-ion batteries
By Kevin Goodman-Rendall
PhD Student Cover Letter At Ethan Scott's Lab- The University of Melbourne
Ethan Scott's Lab- The University of Melbourne
JOIN US! We're seeking a new PhD student in beautiful Melbourne🇦🇺 @UniMelb . Join our diverse
supportive team of physicists
neuroscientists
and mathematicians as study how #zebrafish brains perceive the world. Deadline: May 9th. Details👇. Please RT Gönderiyi çevir ÖÖ 8:26 · 15 Nis 2024 · 10
7 B Görüntülenme Ethan Scott's Lab @LabEthan · 14s Zebrafish and non-zebrafish people are welcome. Internationals and those from underrepresented groups are encouraged to apply. Our lab is a mutually supportive team with positive vibes and an ethic of teamwork
looking for members with the same mindset. If that's you
read on👇 Ethan Scott's Lab @LabEthan · 14s Projects are available in calcium imaging
optogenetics
computational neuroscience
or behavioural analysis. Work can involve fundamental sensory studies in wild-type animals or phenotyping of #autism model animals.Skills & Qualifications • Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. Communication Teamwork Creativity Time management Adaptability Leadership Problem solving Decision-making Interpersonal communication Professionalism Critical thinking Flexibility Conflict resolution Stress managementWe aim to understand how sensory stimuli are perceived and processed in the brain
and how the brain then interprets these stimuli to produce adaptive behaviours. Because of the brain’s extraordinary complexity
these questions are difficult to address by looking at individual cells. The flow of information through the brain relies on the coordinated activity of thousands or millions of cells
and on ensembles of neurons that are active simultaneously. For this reason
our research involves imaging activity in thousands of cells
and seeking salient patterns of activity across these populations. In a range of projects
we characterise the neurons and circuits that respond to various visual
auditory
water flow
and vestibular stimuli; that play a role in the integration of information from these modalities; and that filter sensory information to produce behaviour. Image: Frequency map of brain We work in the zebrafish model system because of its strengths in genetics
behaviour
microscopy
and optogenetics. Specifically
we use transgenic techniques to express genetically encoded calcium indicators (GECIs) or optogenetic proteins in specific parts of the zebrafish brain. We then use selective plane illumination microscopy (SPIM) to observe the GECIs
which reveal activity across our cells and circuits. We also use optical physics to produce holograms in the brain for optogenetics in our larval fish. Gradually
we aim to transition from describing patterns of activity in the brain to manipulating them in targeted ways
and to describing the structures and connectivity of the neurons carrying the information. This will contribute to a comprehensive understanding of brain function spanning cells
circuits
regions
and the brain as a whole.
By Melike Cansel EREN
Phd student Cover Letter At Institute of Laboratory Medicine, Clinical Chemistry and Molecular diagnostics
Institute of Laboratory Medicine, Clinical Chemistry and Molecular diagnostics
By Negin
Ph.D. Student Cover Letter At Department of Mechanical Engineering at University of Alberta
Department of Mechanical Engineering at University of Alberta
By Arian Hosseini
PhD Student Cover Letter At Glia Lab Oslo Un
Glia Lab Oslo Un
Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis. Research Goals In addition to the 85 billion neurons in the brain
we find at least as many glial cells. The research focus of GliaLab is to discover physiological roles of a subtype of glial cells called astrocytes
in the awake-behaving and sleeping brain as well as identifying roles of astrocytes in brain disorders. Astrocytes serve a wide array of functions in the brain. On the one hand
they are caretakers of the brain by controlling the composition of the extracellular fluids. In particular they are key for removing excess neurotransmitter and K+ in relation to neuronal activity. Moreover
they display a rich repertoire of cellular signaling
that likely enable them to more direcly interact with neurons. Our main research interests are as follows: What are the roles of astrocytic Ca2+ signals in sleep and brain state changes? Since the discovery that astrocytes can react with and communicate by local or spreading Ca2+ elevations
a range of different mechanisms have been linked to these signals. For instance
such signals have been proposed to influence neuronal network activity by release of transmitter substances in
or close by
synapses. Similarly
astrocytic Ca2+ signals have been proposed to influence vascular tone. Currently
we're trying to outline the role of astroglial Ca2+ signals in brain/sleep state changes and in memory encoding and consolidation. How does the extracellular fluid circulate in the brain parenchyma? In 2013 a seminal paper described extracellular fluid may circulate from the perivascular spaces of artieries
through the parenchyma
before exiting the brain
taking waste products with it. This circulation system
or 'brain washing' system
was coined the 'glymphatic system'
and was proposed to play a role in Alzheimer's disease pathophysiology. To answer these questions we work with advanced imaging techniques. Most importantly
two-photon microscopy in awake head-fixed mice
in combination with electrophysiology and molecular strategies. What are the astrocytic mechanisms involved in cortical spreading depression (CSD) and epilepsy? CSD is the phenomenon underlying the perceptual disturbances of the migraine aura
and although first discovered over 70 years ago
key aspects of these events are still unknown. We are currently trying to identify the roles of astrocytes in CSD. We are also investigating putative roles of astrocytes in seizure propagation and in epileptogenesis.
By Melike Cansel EREN
phd student Cover Letter At university of chester
university of chester
By Taniya Singh
PhD student Cover Letter At academic journal
academic journal
By SH
PhD student Cover Letter At University College Dublin Department: School of Veterinary Medicine
University College Dublin Department: School of Veterinary Medicine
• Isolated stem cells were isolated from the femur bone of healthy experimental animals. A primary hematopoietic cell line was obtained in cell culture. Primary neuron culture was tried to be received with cells taken from the olfactory bulb. • Cared for and fed rabbits
rats
and mice (including transgenic and nude mice). Conducted health checks and monitored their well-being. Worked in the animal production center
overseeing their mating
monitoring birth
and providing care for offspring. Conducted maternal immune activation while modeling autism spectrum disorder and multiple sclerosis disease. Completed relevant animal information forms and ensured the availability of normal controls. • Placed catheters in animals as required for ongoing projects
established vascular access
performed injection procedures
and administered gavage applications for feeding. Assisted in conducting stereotaxic surgery procedures. • Carried out behavioral experiments related to ongoing projects on MI
Parkinson's disease
Alzheimer's disease
autism spectrum disorder
and schizophrenia. Utilized various tests such as open field
Morris Water maze
Ratorot test
maze tests
passive avoidance test
locomotor activity test
grip strength measurement test
hot-cold plate test
odor discrimination test
social recognition test
pre-stimulus-mediated inhibition test
pole test
grid test
and shuttle box test. • Analyzed behavioral test data using SPSS and MATLAB. • Participated in molecular and histological studies by sacrificing animals as deemed appropriate by the ethics committee at the end of experiments. • Isolated stem cells from the femur bone of healthy experimental animals. Obtained a primary hematopoietic cell line in cell culture. Attempted to establish a primary neuron culture using cells from the olfactory bulb.• Investigated the behavioral and physiological effects of long-term high fructose corn syrup diets in rats. Utilized histological and molecular techniques to evaluate attention deficit in rats. • Evaluated the positive reinforcement effect of taurine by conducting the operant box test in rats and compared the behavioral outcomes of caffeine and taurine. • Provided animal production
care
and feeding for rats and mice. Gained experience in stereotaxic surgery and dissection procedures. • Developed a project on the effects of orexin-saponin-induced septohippocampal neurodegeneration on sensorimotor gating and long-term memory. Successfully secured funding for the project.• Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis.
By Melike Cansel EREN
PhD Student Cover Letter At Sephton Lab
Sephton Lab
• Ability to work independently and efficiently. • Strong organizational and task prioritization skills. • Excellent communication skills and proficiency in performing administrative and clerical tasks. • Proficient in general laboratory procedures
techniques
and documentation. • Willingness to learn and adapt to new techniques and technologies. • Fluent in English
Spanish
French
and Catalan. • Proficient in statistical analysis and software such as SPSS
MATLAB
and Python. • Proficient in using various software programs
including Microsoft Office Suite (Word
Excel
PowerPoint). • Advanced knowledge and experience in 3D cell culture techniques. • Skilled in protein isolation
Western Blot
PCR
rt-qPCR
toxicity testing
IHC
Northern Blot
and ELISA. • Proficient in anatomical dissection studies for medical and veterinary purposes. • Experienced in static analysis of behavioral data and microarray data. • Familiarity with electrophysiology
imaging
protein purification
and optical and electron microscopy techniques. • Advanced level proficiency in conducting animal experiments
behavioral experiments
anatomical dissection
and molecular analysis.An early clinical feature of ALS is an imbalance in energy homeostasis
which leads to an overall energy deficit. Due to the high energy demands and impaired glucose metabolism that occurs in ALS
there is a metabolic switch from glucose to lipids for energy production in the central nervous system. The successful candidate will lead a project investigating the cause and impact of this metabolic switch in the brain and spinal cord using animal models and cell-culture models of ALS/FTD. Utilizing methods like immunohistochemistry
confocal microscopy
neuron-glia co-cultures
western blotting and lipid and protein mass-spectrometry
the project aims to elucidate how the central nervous system manages lipids as an energy source and whether it is impaired in familial models of ALS
contributing further to the pathogenesis of disease.
By Melike Cansel EREN